Saturday, May 16, 2009

Wolfram|Alpha: Future of search and analysis

This is something very interesting I came across recently. I have just seen the DEMO which is so mind blowing, actual site is located here Wolfram|Alpha. God!!! we are a growing species, I just have to say that it is just mind blowing....marvelous..yes we human ...mind is the speck over the hell to achieve unimaginable through the labyrinthine network of our neuronal circuit ..its evitable the more guttural pouch will emerge like this..which will be more useful in days to come...This is the future of the way we look at the internet today, the search we do over internet, The search results and their analysis, which otherwise takes us to 100s of pages with analysis for the required details over each page. Anyways, this Wolfram|Alpha looks so good and I am wondering that it came bit late. Very amazing piece of work, I am sure this is going to be very very useful to almost every internet user. I am also hopeful that as in comparison to the Google search results ,this gives more analyzed results. And no I am not comparing these two. Lots of mathematical calculation, lots of general work analysis. I am sure Wolfram|Alpha people are and will be having tough time maintaining such a brilliant technology.

Tuesday, March 31, 2009

miRex: A web based resource for miRNA expression profiles

Background: A few hundred miRNAs carry the potential to regulate thousands of target genes in eukaryotes. The expression profiles of miRNAs convey important information regarding tissue specific gene expression and can be used as a biomarker for disease progression and cancer classification among other rational interpretations pertaining to miRNA-gene interactions. There are several individual reports of miRNA expression profiling; however there is a lack of server that can render cross-comparison of all these datasets.


Description: We have developed miRex, a database and analysis tool for comparing miRNA expression profiles generated by high-throughput methods. Currently data from public repositories have been pre-normalized and provided with visual representation to aid comparison between experiments. miRNA ID converter: a tool for mapping miRNA IDs from one system of nomenclature to another has also been included.


Data: Currently, 614 experiments spanning 25 datasets deposited in Gene Expression Omnibus (GEO),the public repository for high-throughput gene expression data hosted by NCBI and 1132 experiments from 18 datasets from ArrayExpress, another resource for expression data, is available through miRex. Besides the microarray based data, there is a set of 40 experiments carried out by real time PCR.


URL: miRex is available at http://miracle.igib.res.in/mirex/


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